Human Growth Hormone
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چکیده
1. Children with proven growth hormone deficiency (GHD) 2. Children with height less than 3rd percentile for chronologic age with chronic renal insufficiency 3. Patients with AIDS wasting 4. Adults with proven GHD 5. Patients with Turner’s syndrome 6. Children with growth failure due to Prader-Willi syndrome 7. Patients with short stature due to Noonan syndrome 8. Promotion of wound healing in burn patients 9. Prevention of growth delay in children with severe burns 10. Patients with short bowel syndrome receiving specialized nutritional support in conjunction with optimal management of short bowel syndrome 11. Children with short stature due to SHOX (short stature homeobox-containing gene) deficiency.
منابع مشابه
Evaluation of Heat Induction Strategy for Recombinant Human Growth Hormone Expression in Fed-Batch Fermentation
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Using L-arabinose for Production of Human Growth Hormone in Escherichia coli, Studying the Processing of gIII::hGH Precursor
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CONSTRUCTION OF RECOMBINANT PLASMIDS FOR PERIPLASMIC EXPRESSION OF HUMAN GROWTH HORMONE IN ESCHERICHIA COLI UNDER T7 AND LAC PROMOTERS
In order to study the periplasmic expression of human growth hormone (hGH) in Escherichia coli, the related cDNA was inserted in two expression plasmids carrying pelB signal peptide, one with lac bacterial promoter and the other with a bacteriophage T7-based promoter. The recombinant plasmids were moved to TG1 and BL21 strains of E. coli, respectively. To induce the expression systems, IPTG and...
متن کاملA Microcalorimetry Study of the Binding of Nickel Ion by Human Growth Hormone
A binding study of nickel ions by a new recombinant human Growth Hormone (hGH), produced as an injected drug, has been done at 27˚C in NaCl solution (50 mM) using an isothermal titration calorimetry. There is a set of three identical and non-interacting binding sites for nickel ions. The intrinsic dissociation equilibrium constant and the molar enthalpy of binding are 40 μM and -16...
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The interaction of hGH with some metal ions ( ) at 27°C in NaC1 solution, 50 mM was studied using Isothermal titration calorimetry. There is a set of three identical and non-interacting binding sites for binding of all these metal ions, expect . The intrinsic association equilibrium constants () are not very different for and , and also their molar enthalpies of binding (KJ/mol for and KJ/mo...
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